FIGURE

Figure 5

ID

ZDB-FIG-230515-93

Publication

Arroyo et al., 2023 - NAMPT and PARylation Are Involved in the Pathogenesis of Atopic Dermatitis

Other Figures

All Figure Page

Back to All Figure Page

Figure 5

Reduction in pathology-associated biomarkers in human organotypic 3D skin model of AD. (A) Experimental design. Transcript levels of the indicated genes encoding markers of inflammation (B–D,H), epidermal differentiation (E,F) and proliferation (G) were determined in human organotypic 3D skin pretreated with 10 ng/mL IL13 and IL4 in the presence of vehicle (DMSO) or the indicated inhibitors. Protein levels of interest were also determined by Western blot (I,J). The mean ± SEM of each group is shown. Results are representative of 3 independent experiments. p values were calculated by Kruskal–Wallis test and Dunn’s multiple comparisons test. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001. M, molecular weight markers.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.