FIGURE

Fig. 6

ID

ZDB-FIG-230427-55

Publication

Seda et al., 2023 - A CRISPR/Cas9-generated mutation in the zebrafish orthologue of PPP2R3B causes idiopathic scoliosis

Other Figures

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Fig. 6

Temporal analysis of cartilage. Articular cartilage within the hypural bones is lost by 36 dpf (A, arrows) in ppp2r3b^−/− mutants but forms normally at 15 dpf (B) and is maintained until 26 dpf (C). Within the vertebral bodies, cartilage is induced and maintained normally (D, E) and is replaced by mineralised bone by 36 dpf (A, and data not shown) in mutants. Scales bars are (A) 2.5 mm, (B) 0.5 mm, (C) 2.5 mm, (D) 150 µm, (E) 5 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ppp2r3b^u1001/u1001
Observed In:	hypural articular cartilage
Stage Range:	Days 14-20 to Days 30-44

Phenotype Detail

Acknowledgments

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