FIGURE

Fig. 5

ID

ZDB-FIG-230427-54

Publication

Seda et al., 2023 - A CRISPR/Cas9-generated mutation in the zebrafish orthologue of PPP2R3B causes idiopathic scoliosis

Other Figures

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Fig. 5

(A) Bright field images and (B) microCT scans of representative wild-type or homozygous ppp2r3b^−/− mutant zebrafish at 36 or 48 dpf. White arrows in (B) point to sharp lateral curvatures of the spine. (C) Quantification of the proportion of animals with mild, moderate or severe kyphoscoliosis. Numbers of animals are given. Scale bars are 5 mm. All animals were generation F4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ppp2r3b^u1001/u1001
Observed In:	caudal fin caudal vertebra precaudal vertebra vertebral column
Stage Range:	Days 30-44 to Days 45-89

Phenotype Detail

Acknowledgments

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