FIGURE

Figure 1

ID

ZDB-FIG-230406-82

Publication

Rolland et al., 2022 - The regenerative response of cardiac interstitial cells

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Figure 1

scRNA-seq analysis of regenerating zebrafish hearts. (A) Schematic of our scRNA-seq pipeline. (B) UMAP clusters of the different populations of cells and sub-clusters identified in zebrafish hearts. The graph shows the proportion of all the cells within individual clusters at each timepoint, e.g. EC1 contains 20% of all the cells in an uninjured ventricle, which drops to ∼5% at 3 dpa. ER, erythrocytes. (C) A DotPlot shows the 5 genes used to characterize the different cell types. (D–F) UMAP plot indicates the cluster of proliferating cells based on the expression of mki67. (E) The cluster pointed by the black arrow is shown at higher magnification. (F) The proliferating cluster shown contains mfap4⁺ myeloid cells (macrophages) and mfap4^–lymphoid cells.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Mol. Cell Biol.