FIGURE

Figure 3

ID

ZDB-FIG-230228-266

Publication

Liu et al., 2023 - Gata2a Mutation Causes Progressive Microphthalmia and Blindness in Nile Tilapia

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Figure 3

Morphological analysis of tilapia gata2a mutants at 90 dpf. (A) Morphology of gata2a mutants. (B) Proportions of the fish with microphthalmia in the F2 generation. (C) Eyes morphology of the gata2a mutants at 90 dpf. The presence of small eyes on the left or right side is random in gata2a^+/− fish. (D,E) Body weight and body length (sample size: homozygous mutants, n = 8, heterozygous mutants, n = 50, wt, n = 23). (F) Eye morphology of gata2a homozygous mutants at 180 and 360 dpf. (G,H) Eyes axial length and lens diameter. Data are expressed as the mean ± SD. One-way ANOVA was performed followed by Tukey’s test. Different letters above the error bar indicate significant differences at p < 0.05. dpf: day post fertilization. “gata2a^+/−-s” and “gata2a^+/−-b” represents eyes from gata2a heterozygous mutants with unilateral micropgthalmia (s, small eye; b, big eye).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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