FIGURE
Fig. 1
- ID
- ZDB-FIG-230219-28
- Publication
- Albert et al., 2022 - Bistable Photoswitch Allows in Vivo Control of Hematopoiesis
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Fig. 1
Design and synthesis of CS-VIPs. (A) Photoswitchable MM-401 cyclopeptides. (B) Exemplified synthesis for CS-VIP 8. (i) 1.00 equiv Pd(PPh3)4, 190 equiv morpholine, DCM, 2 h, rt; (ii) 4.00 equiv Oxyma, 4.00 equiv DIC, 4.00 equiv Mtt-oF4Azo, DMF, 45 min, rt; (iii) HFIP/DCM 1:4, 2 h, rt; (iv) 3.00 equiv HATU, 4.00 equiv DIPEA, THF/DMF 98:2, 45 min, rt, at 520 nm 3 min; (v) 4 M HCl in dioxane, 3 h, rt; d-Dap d-diaminopropionic acid, d-Dab d-diaminobutyric acid, Abu aminobutyric acid, SPPS solid phase peptide synthesis. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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