FIGURE

Fig. 6

ID
ZDB-FIG-230205-25
Publication
Marcogliese et al., 2022 - Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling
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Fig. 6

Reprogrammed astrocytes from NEDAMSS patients display increased WNT1 transcription and protein.

(A to C) WNT1 transcript (A) and protein (B and C) are elevated in reprogrammed astrocytes derived from fibroblasts of NEDAMSS patients and healthy controls by qPCR (A), immunofluorescence (B), and Western blot (C). RFE, relative fold expression. ANOVA followed by Dunnett’s multiple comparison test between the mean of the controls and the mean of each line was computed to derive the P value: *P < 0.05 and ****P < 0.0001. The experiments were conducted three times. Scale bar, 20 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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