Image
|
Figure Caption
Fig. 6
Reprogrammed astrocytes from NEDAMSS patients display increased WNT1 transcription and protein.
(A to C) WNT1 transcript (A) and protein (B and C) are elevated in reprogrammed astrocytes derived from fibroblasts of NEDAMSS patients and healthy controls by qPCR (A), immunofluorescence (B), and Western blot (C). RFE, relative fold expression. ANOVA followed by Dunnett’s multiple comparison test between the mean of the controls and the mean of each line was computed to derive the P value: *P < 0.05 and ****P < 0.0001. The experiments were conducted three times. Scale bar, 20 μm.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Sci Adv