Figure 5
- ID
- ZDB-FIG-230110-140
- Publication
- Jim et al., 2022 - Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq
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Transcriptional response in pneumolysin-positive or pneumolysin-negative S. pneumoniae D39V (A) Pneumolysin-specific transcriptional rewiring in S. pneumoniae in response to injection in zebrafish embryo. Fold change of transcriptional response in S. pneumoniae PLY+ and PLY− is plotted against its genomic location. (B) Fold change of ComX regulons between S. pneumoniae PLY+ and S. pneumoniae PLY− strains shows gene expression regulation in response to zebrafish infection. ssbB, a member of the regulon shows increased expression in S. pneumoniae PLY+ compared with S. pneumoniae PLY− (FC ≥ 2.0, q < 0.5). Regulons are sorted by fold change value in descending order. |