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Figure 5

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ZDB-IMAGE-230110-143
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Figures for Jim et al., 2022
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Figure 5

Transcriptional response in pneumolysin-positive or pneumolysin-negative S. pneumoniae D39V

(A) Pneumolysin-specific transcriptional rewiring in S. pneumoniae in response to injection in zebrafish embryo. Fold change of transcriptional response in S. pneumoniae PLY+ and PLY− is plotted against its genomic location.

(B) Fold change of ComX regulons between Spneumoniae PLY+ and S. pneumoniae PLY− strains shows gene expression regulation in response to zebrafish infection. ssbB, a member of the regulon shows increased expression in Spneumoniae PLY+ compared with S. pneumoniae PLY− (FC ≥ 2.0, q < 0.5). Regulons are sorted by fold change value in descending order.

Acknowledgments
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