FIGURE
            Figure 7
- ID
- ZDB-FIG-221214-88
- Publication
- Wang et al., 2022 - Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity
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                        Figure 7
                    
                    
                
                
            
        
        
    
        
            
            
| 
 Disruption of SMYD3 protects cells against hypoxia-induced apoptosis. A, apoptotic cells in Smyd3-deficient or wildtype MEF cells (Smyd3−/− or Smyd3+/+) under normoxia or hypoxia detected by flow cytometry analysis. Data show mean ± SD; Student’s two-tailed t test. ∗∗p < 0.01. Data from three independent experiments. B, apoptotic cells in Smyd3-deficient or wildtype MEF cells (Smyd3−/− or Smyd3+/+) under normoxia or hypoxia detected by fluorescence microscopy. Scale bar = 100 μm. MEF, mouse embryonic fibroblast. | 
                
                    
                        Expression Data
                    
                    
                
                
            
        
        
    
        
            
            
            
            
    
    
                
                    
                        Expression Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Antibody Labeling
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype Data
                    
                    
                
                
            
        
        
    
        
            
            
            
            
    
    
                
                    
                        Phenotype Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Acknowledgments
                    
                    
                
                
            
        
        
    
        
            
            
                
                    
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      Full text @ J. Biol. Chem.
                
                
            
        
        
    
    
     
        