FIGURE

Figure 3

ID

ZDB-FIG-221214-223

Publication

Kang et al., 2022 - Disruption of the glucagon receptor increases glucagon expression beyond α-cell hyperplasia in zebrafish

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Figure 3

KO of GCGR in zebrafish increased glucagon expression in α-cells.A and B, the plots show the expression of glucagon genes (A) and their regulators (B). The color scale ranges gray to blue corresponding to expression level from low to high; all plots are based on cell clusters shown in Fig. 1B. C, the violin plots show gcga and gcgb relative expression in α-cells from control and gcgr^−/− zebrafish. D, heatmap of differentially expressed genes (DEGs) of gcgr^−/− compared to control cells; the color scale ranges red to blue corresponding to expression level from low to high. E, pathway enrichment analysis of DEGs between gcgr^−/− and control cells. GCGR, glucagon receptor.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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