FIGURE

Figure 1

ID
ZDB-FIG-221214-205
Publication
Janoš et al., 2022 - Role of Monovalent Ions in the NKCC1 Inhibition Mechanism Revealed through Molecular Simulations
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Figure 1

(A) Full length dimeric structure of zebrafish (z)NKCC1. (B) The monomeric transmembrane model of zNKCC1. NKCC1 is depicted as magenta, yellow, blue, cyan, and white new cartoons for α-helix, β-sheet, 310-helix, turn and coil elements, respectively. The Cl, Na+, and K+ ions are shown as cyan, blue, and orange van der Waals spheres, respectively. The hydrophilic head groups and hydrophobic tails of the phosphatidylcholine lipids are depicted in light blue and white surfaces, respectively. (C) Sketches of the four investigated NKCC1 inhibitors.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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