FIGURE

Fig. 6

ID

ZDB-FIG-221207-18

Publication

Jia et al., 2022 - Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish

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Fig. 6

Schematic summary of the main findings in this study.

Depletion of Tulp1a and Tulp1b in zebrafish diminished the transcriptional activity of tekt2, which impaired the ciliogenesis of photoreceptors, and thus interfering the trafficking of opsins. Eventually, ferroptosis was activated in photoreceptors, and retina was degenerated.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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