FIGURE

Figure 3

ID

ZDB-FIG-221118-35

Publication

Edirisinghe et al., 2022 - Effect of Polydeoxyribonucleotide (PDRN) Treatment on Corneal Wound Healing in Zebrafish (Danio rerio)

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Figure 3

Histological analysis of zebrafish eye and corneal re-epithelialization following the corneal injury and PDRN treatment. (A) Representative image of H&E stained zebrafish eye, cornea, and graphical illustration of the corneal epithelium. (B) Representative photograph of the whole eye of un-injured (negative control), cornea-injured vehicle, and cornea-injured PDRN-treated groups (scale bars, 40 μm), and (C) photographs of selected central epithelium surface of the cornea (scale bars, 200 μm.) at 1 and 72 hpi. Regenerated epithelial cell layers were marked with black arrows. Quantification of corneal regeneration based on (D) epithelium thickness, and (E) number of epithelium cell layers at 72 hpi. One-way ANOVA was performed to determine the statistical significance; * p < 0.05, ** p < 0.01, *** p < 0.001 (n = 8).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical ablation: corneal epithelium, chemical treatment: single-stranded DNA polynucleotide chemical ablation: corneal epithelium
Observed In:	corneal epithelium
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.