Fig. 5
- ID
- ZDB-FIG-221025-6
- Publication
- Hu et al., 2021 - A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model
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Fig. 5. L72 treatment inhibited STAT3 in HEL cells. (A) 3D interactive autodock image showing the interaction of pimozide with STAT3. (B) 3D interactive autodock image showing the interaction of L72 with STAT3. (C) 2D image showing amino acids interrelating between pimozide with STAT3. (D) 2D image showing amino acids interacting between L72 with STAT3. (E) Interaction parameters of pimozide and L72 with STAT3. (F) The protein expression of STAT3 after L72 treatment at the indicated doses for 24 h. GAPDH is used as a loading control. (G) The protein expression of STAT3 after DMSO, L72 (20 µM), pimozide (10 µM), L72 (20 µM) + Pimozide (10 µM) treatment at 6 (G) and 12 h (H) of incubation. GAPDH is used as a loading control. The relative densities (RD) normalized with GAPDH. |