FIGURE

Fig. 6

ID

ZDB-FIG-220908-35

Publication

Chen et al., 2022 - Cysteamine affects skeletal development and impairs motor behavior in zebrafish

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Fig. 6

Notch signal rescued the skeletal development defects caused by cysteamine. (A) Tg (tp1: GFP) microscopic imaging of zebrafish larvae exposed to 0.35, 0.70, and 1.05 mM cysteamine, and 1.05 mM cysteamine with 60 μM sodium valproate at 72 hpf. (B) Tg (tp1: GFP) fluorescence intensity of zebrafish larvae exposed to 0.35, 0.70, and 1.05 mM cysteamine, and 1.05 mM cysteamine with 60 μM sodium valproate at 72 hpf. (C) Expression analysis of genes related to Notch signaling pathway. (D) Microscopic imaging of zebrafish Tg (twhh: GFP) larvae exposed to 1.05 mM cysteamine, and 1.05 mM cysteamine with 60 μM sodium valproate at 72 hpf. Scale bars: 100 μm (A), 50 μm (D). *p < 0.05, **p < 0.01, ***p < 0.001, mean ± S.D.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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