FIGURE
FIGURE 5
- ID
- ZDB-FIG-220903-5
- Publication
- Risato et al., 2022 - Hyperactivation of Wnt/β-catenin and Jak/Stat3 pathways in human and zebrafish foetal growth restriction models: Implications for pharmacological rescue
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FIGURE 5
Stat3 signalling modulation does not rescue FGR anomalies. Downregulation of Stat3 signalling with 50 μM AG490 inhibitor does not rescue body length, eye size and cardiac morphology under hypoxia. Upregulation of Stat3 signalling with 20 μM LIF agonist does not rescue body length, eye size and cardiac morphology under hypoxia. All embryos, at 3 dpf, are displayed in lateral view, anterior to the left. Sample size: |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Front Cell Dev Biol