FIGURE

Figure 1

ID

ZDB-FIG-220730-25

Publication

Petersen et al., 2022 - Evolution and developmental expression of the sodium-iodide symporter (NIS, slc5a5) gene family: Implications for perchlorate toxicology

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Figure 1

Maximum‐likelihood phylogenetic tree of Slc5a aligned amino acid sequences in representative vertebrate taxa. Phylogenetic analysis used a LG + G + F substitution model. A maximum‐likelihood tree inferred using PhyML (see Section 2) rooted here on the CHT clade. Numbers at nodes indicate bootstrap support (among 100 replicates). Protein names omit ”Slc”. Human and stickleback proteins are highlighted in blue and red, respectively. Results identified three main clades: the NIS (sodium–iodide symporter) clade at the top, the SGLT (sodium–glucose cotransporter) clade in the middle, and the slc5a7 clade. Dre, Danio rerio; GAC, Gasterosteus aculeatus; Hsa, Homo sapiens; Loc, Lepisosteus oculatus; Mus, Mus musculus

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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