FIGURE

Fig. 5

ID

ZDB-FIG-220722-7

Publication

Rusnati et al., 2021 - Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin

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Fig. 5

Effect of UniPR1331 on VEGF-induced VE-cadherin internalization and permeabilization in ECs.

a HUVECs unstimulated or stimulated with VEGF and UniPR1331 were analyzed for VE-cadherin internalization by WB. b Microphotographs of GM7373-VEGFR2 cells incubated with VEGF and UniPR1331 and immunostained for VE-cadherin (scale bar: 10 μm). c Monolayer of GM7373-VEGFR2 cells unstimulated or stimulated with VEGF and UniPR1331 were evaluated for permeability as described in “Material and methods.” The results shown are the mean ± S.E.M. of three independent experiments; *P < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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