FIGURE

Fig. 1

ID

ZDB-FIG-220720-107

Publication

Meier et al., 2022 - Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish

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Fig. 1

Alternative G-CSFR pathways in myelopoiesis. (A?D) Fluorescent microscopy images of representative 22 hpf Tg (mpo::GFP) embryos injected with either scr Mo (A), csf3a Mo (B), csf3b Mo (C) or csf3r Mo (D). (E,G) Quantitation of the number of mpo+ cells in embryos injected with morpholinos (E) or treated with specific inhibitors (G). (F,H) Quantitation of relative migration of mpo+ cells in embryos injected with morpholinos (F) or specific inhibitors (H). (I?L) Fluorescent microscopy images of representative 48 hpf Tg (lyz::DsRed) embryos injected with either scr Mo (I), csf3a Mo (J), csf3b Mo (K) or csf3r Mo (L). (M,N) Quantitation of lyz+ cells in embryos injected with morpholinos (M) or specific inhibitors (N). In panels E?H and M?N, results are shown for individual embryos along with mean and SEM in red, with the level of statistical significance relative to controls indicated (*: p $<$ $<$ 0.05; **: p $<$ $<$ 0.001; ***: p $<$ $<$ 0.0001; ns, not significant).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Biosci (Landmark Ed)