Fig. 5
- ID
- ZDB-FIG-220628-33
- Publication
- Lin et al., 2022 - The Extracts of Polygonum cuspidatum Root and Rhizome Block the Entry of SARS-CoV-2 Wild-Type and Omicron Pseudotyped Viruses via Inhibition of the S-Protein and 3CL Protease
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PCRREtOH and PCRRwater inhibit the entry of wild-type pseudovirus. The F-actin component of the cell membrane was stained with fluorescent phalloidin. The intensity of ZsGreen fluorescence in the cells was measured with ImageJ after treatment with PCRREtOH (0.1 mg/mL) or PCRRwater (0.1 mg/mL). The fluorescence intensity was considerably reduced when compared with the control group with no drug treatment. A SARS-CoV-2 neutralizing antibody (1 µg/mL) was utilized as a positive control. These are representative images; n = 3. In each image, the region marked with the asterisk is shown at a higher magnification in the inset panel. |