FIGURE

Fig. 11

ID

ZDB-FIG-220628-24

Publication

Oliva et al., 2022 - Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents

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Fig. 11

Effects of 8q treatment on the zebrafish xenotransplantation model. (A): Representative images of Tg(fli1:EGFP) zebrafish embryos (with GFP-positive blood vessels) transplanted with DiI+ HeLa cells (red). Embryos were treated for 24 h with DMSO (control group), 290 nM 8q, or 145 nM 8q. The trunk region (dashed squares) of each animal was analyzed. Scale bar: 500 μm on the left, and 100 μm for higher magnifications on the right. (B): histograms represent the fluorescence intensity of the tumor xenografts, indicating total HeLa cells presents in each embryo after a 24 h treatment with 8q at the indicated concentrations. Data are expressed as mean ± SD (* p < 0.05, ** p < 0.01).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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