FIGURE

Fig. 8

ID

ZDB-FIG-220623-62

Publication

Figueiredo et al., 2022 - Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses

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Fig. 8

Fig 8. Full encapsulation of the cells is necessary for virulence.

A) Survival graph of zebrafish embryos injected, three days post-fertilization, with wild-type ATCC6314 (WT), unencapsulated BCSMC001 (?cps), wzd null mutant BCSMH001 (?wzd) and medium used to resuspend bacteria (Control). The wzd null mutant was severely impaired in virulence, similarly to the unencapsulated BCSMC001 strain. The assay was performed with at least 50 embryos for each condition that were injected in four different days and the obtained survival curves, except those obtained with the cps and wzd mutants, were significantly different (p<0.0001). (hpi) hours post infection.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	bacterial treatment by injection: Streptococcus pneumoniae
Observed In:	whole organism
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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