FIGURE
Fig. 2
- ID
- ZDB-FIG-220621-2
- Publication
- Yu et al., 2022 - A non-polar fraction of Saponaria officinalis L. acted as a TLR4/MD2 complex antagonist and inhibited TLR4/MyD88 signaling in vitro and in vivo
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Fig. 2
SH suppressed NF-κB translocation by reducing the phosphorylation of IκB-α in THP-1 macrophages. THP-1 macrophages were co-treated with SH and LPS (1 μg/ml) for 12 h. (A) Relative phosphorylation of IκB-α and total protein levels as determined by western blot. (B) Nuclear translocation of NF-κB (p65) as determined by western blot, and (C) visualized by immunofluorescence microscopy. Results are presented as the means ± SDs of three different experiments. ##p < .01 versus non-treated control macrophages, and *p < .05, **p < .01 versus LPS-treated control macrophages.
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Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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