FIGURE

Fig. 1

ID

ZDB-FIG-220620-42

Publication

Luo et al., 2022 - The inhibition of protein translation promotes tumor angiogenic switch

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Fig. 1

Angiogenic switch model in zebrafish. a Imaging of the tumor vascular growth with a confocal microscope. The first column indicates that the transplant microtumor does not yet have blood vessels (No vessel, Avascular phase). The second and third columns indicate the presence of blood vessels in the transplant microtumor (First vessel, Vessel network; Vascular phase). Endothelial cells (ECs) are green. Tumor is red. Yellow line, host vessel. White arrow, tumor vessel. Scale bar, 50 μm. b The branches and c length of tumor vessels and d tumor volume post tumor cells transplant for 72 h (n = 6). Light blue shade, avascular stage. Light orange shade, vascular stage. Light black curved arrow, angiogenic switch. e. Survival curve for zebrafish with or without transplant tumor cells for 10 days (n = 20). Log-rank (Mantel-Cox) test, *** P < 0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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