FIGURE

Figure 2

ID

ZDB-FIG-220430-31

Publication

Li et al., 2022 - Profilin 2 and Endothelial Exosomal Profilin 2 Promote Angiogenesis and Myocardial Infarction Repair in Mice

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Figure 2

Exosomal PFN2 repairs infarction in mouse with MI and restores cardiac function. (A) The cardiac function of mouse with MI as evaluated by type-B ultrasonic test EF and FS after treatment with exosomes demonstrated the benefit to MI impairment. (B) Physical fitness was evaluated by fatigue test after treatment with exosomes in mouse with MI which displayed significant improvement of heart function, n = 7. (C) Infarction volume (Masson's staining) decreased and PFN2 (green)/CD31 (red) staining increased in heart tissue of mouse with MI after treatment with exosomes. (D) Statistical results of (C). n = 3, normalized to control. *p < 0.05, one-way ANOVA (Tukey).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cardiovasc Med