FIGURE

Figure 1

ID

ZDB-FIG-220430-30

Publication

Li et al., 2022 - Profilin 2 and Endothelial Exosomal Profilin 2 Promote Angiogenesis and Myocardial Infarction Repair in Mice

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Figure 1

Increased PFN2 and exosomal PFN2 levels in the serum of patients with MI and in animal models. (A) Enhanced PFN2 levels, VEGFA and bFGF levels in patients with MI (patients with MI 2–20 h, n = 30; MI 8–15 d, n = 30; CTL, n = 24). (B) Enhanced PFN2 levels, VEGFA and bFGF levels in pigs with MI (pigs with MI, n = 4; CTL, n = 4). (C) Identification of serum exosomes in patients with MI by electron microscopy. (D) Exosomal PFN2 between CTL (n = 3) and MI groups (n = 3). (E) Exosomal PFN2 levels between CTL (n = 3) and MI groups (n = 3) (The protein level was normalized to control). (F) Serum PFN2 levels, Exosomal PFN2 levels and Exosomes in rats (n = 13) before and after MI. *p < 0.05, one-way ANOVA and repeated-measures ANOVA (Tukey).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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