FIGURE

FIG 3

ID

ZDB-FIG-220430-137

Publication

Lin et al., 2022 - WhiB4 Is Required for the Reactivation of Persistent Infection of Mycobacterium marinum in Zebrafish

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FIG 3

The whiB4::Tn mutant induces lower levels of host immune response than the WT strain. RNA-seq analysis of kidneys isolated from zebrafish infected with whiB4::Tn or WT at 2 weeks postinfection was performed. The identified DEGs were subjected to GO analysis (A) and KEGG pathway analysis (B). Each circle represents a biological process or pathway, and the size of the circle is proportional to the number of genes detected. (C) Map DEGs involved in the cytokine-cytokine receptor interaction pathway. Green, downregulated; red, upregulated. (D) RT-qPCR validation of selected DEGs. Heatmap of 18 DEGs analyzed by RT-qPCR. The mRNA levels were normalized against WT and 18S rRNA was used as an internal control. COM, the complemented strain.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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