FIGURE

Fig 2

ID

ZDB-FIG-220415-20

Publication

Madelaine et al., 2020 - Genetic deciphering of the antagonistic activities of the melanin-concentrating hormone and melanocortin pathways in skin pigmentation

Other Figures

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Fig 2

Mammalian orthologous MCH2 peptide induces melanosome contraction.

(A-C) Dorsal melanocytes of control (A), Tg(hs:mch1) (B) or Tg(hs:mch2) (C) black adapted larvae at 7 dpf following heat-shock. (D) Melanosome coverage was quantified in control, Tg(hs:mch1) or Tg(hs:mch2) in region of interest (ROI). The ROI has been defined as an area from the posterior of the eyes to the posterior of the hindbrain. Error bars represent s.d. *P<0.05, **P<0.001, ***P<0.0005, determined by t-test, two-tailed.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT zf3412Tg zf3580Tg
Condition:	heat shock
Observed In:	integument background adaptation melanocyte cellular pigment accumulation melanocyte melanosome melanocyte melanosome localization
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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