FIGURE

Fig. 7

ID

ZDB-FIG-220404-7

Publication

Haraoka et al., 2022 - Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis

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Fig. 7

Schematic illustration of the roles and regulation of cellular senescence during primary tumorigenesis.

A newly emerged oncogenic cell becomes senescent and is eliminated from the epithelia. Additional TP53 mutation and tissue damage switches oncogene-induced senescence from suppressor to driver during primary tumorigenesis.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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