FIGURE

FIGURE 4

ID

ZDB-FIG-220305-13

Publication

Huang et al., 2022 - An In Vivo Fluorescence Resonance Energy Transfer-Based Imaging Platform for Targeted Drug Discovery and Cancer Therapy

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 4

Evaluation of the in vivo drug-induced cell apoptosis in xenograft zebrafish by injecting 231-C3 cells into the zebrafish embryos. (A) Fluorescent images of zebrafish injected with 231-C3 cells and incubated with Ponatinib (10 μM) for 24 h. (B) Images of cell apoptosis in 231-C3 labeled zebrafish after 30 μM cisplatin or 2 μM DOX treatment. Arrows indicate the same zebrafishes observed at different time points. Scale bar = 500 μm. (C) Quantification of FRET ratio in zebrafish after 30 μM cisplatin or 2 μM DOX treatment. n = 6 technical replicates. Data are expressed as mean ± s.e.m. n = 7. *p < 0.05, by Student’s t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Bioeng Biotechnol