FIGURE

FIGURE 3

ID

ZDB-FIG-220305-12

Publication

Huang et al., 2022 - An In Vivo Fluorescence Resonance Energy Transfer-Based Imaging Platform for Targeted Drug Discovery and Cancer Therapy

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FIGURE 3

Tipping points of apoptosis in C3 cells during drug treatment. (A) The flow chart for the selection of single-cell colonies from bulk C3 cells. Single cell clones were harvested from bulk cells by serial dilution in 96-well plate and amplification in 48-well plate. (B) Images of DOX-induced cell apoptosis in single-cell colonies of MDA-MB-231-C3 cells. Red circle indicates single-cell imaging of cell apoptosis. (C) Images of DOX-induced cell apoptosis in single-cell colonies of HepG2-C3 cells. Red circle indicates single-cell imaging of cell apoptosis. (D) Time courses of DOX-induced cell apoptosis of single-cell colonies in MDA-MB-231-C3 cells. (E) Time courses of DOX-induced cell apoptosis of single-cell colonies in HepG2-C3 cells. Green and blue lines indicate total and apoptotic cells, respectively. Scale bar = 50 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Bioeng Biotechnol