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ZDB-FIG-220304-54

Publication

Aman et al., 2021 - Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development

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Fig. s1

Finfold and pelvic fin morphometrics (A) Representative sequential images from sp7:EGFP timeseries showing disappearance of the larval fin-fold (orange arrows) in representative euTH and hypoTH individuals. Though fin fold resorption appeared similar morphologically between euTH and hypoTH, it was markedly delayed in hypoTH fish relative to age, SL [a proxy for stage (Parichy et al., 2009)], and pelvic fin outgrowth (orange bracket). Images are scaled to show similar anatomical region and highlight allometry in the growing fish. (B, C) Finfold resorption was delayed in hypoTH animals relative to euTH and completed in significantly larger and older individuals (t9=20.04, t9=21.98, both p<0.0001; n=6 euTH; n=5 hypoTH). (D) Pelvic fins grew more rapidly in euTH fish compared with hypoTH siblings. (E) Following a burst of allometric growth, the pelvic fins grew isometrically in both euTH and hypoTH individuals. Scale bars, (A) 1 mm.

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Reprinted from Developmental Biology, 477, Aman, A.J., Kim, M., Saunders, L.M., Parichy, D.M., Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development, 205-218, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.