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Fig. 2

ID

ZDB-FIG-220202-15

Publication

Thöni et al., 2021 - Therapeutic Nuclear Magnetic Resonance affects the core clock mechanism and associated Hypoxia-inducible factor-1

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Fig. 2

Effects of tNMR, dexamethasone and light on the cell autonomous clocks of zebrafish fibroblast cells Z3: mRNA expression over two circadian cycles of (A) cry1aa, (B) cry2a, (C) clock1a, (D) per1b, and (E) per2; tNMR (left) presented in light blue, dexamethasone DEX (middle) in red, and light irradiation (right) in light orange; presented are means ± SEM, n = 6; asterisks mark significant changes calculated using two-way ANOVA (GraphPad Prism version 6.00). Cosinor analysis was applied using GraphPad Prism version 6.00, as outlined in detail in Oliva et al. (2018). Circadian oscillations of light treated cells are indicated by an additional light orange cosine wave. Circadian oscillations of unsynchronized zebrafish cells kept under constant darkness (in black) show two acrophases per circadian cycle, as previously reported in Oliva et al. (2018)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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