FIGURE

FIGURE 8

ID

ZDB-FIG-211216-197

Publication

Sun et al., 2021 - Angiogenesis, Anti-Tumor, and Anti-Metastatic Activity of Novel α-Substituted Hetero-Aromatic Chalcone Hybrids as Inhibitors of Microtubule Polymerization

Other Figures

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FIGURE 8

Effect of 7m on the human umbilical vein endothelial cells (HUVECs) migration, invasion, and tube formation. (A) Representative images depicting the vascular structure formation of HUVECs by treatments with 7m for 6–8 h. (B) Scratches were created and images were captured using phase-contrast microscopy at 0 and 48 h after treatments with 7m at different concentrations (1, 5, and 25 µM) or 1% DMSO. (C) The invasion suppressing effects of 7m against HUVECs by Transwell assay. (D) Quantitative evaluation of indicated concentrations of 7m on standard parameters of HUVEC tubule formation. Mean ± SEM of three experiments. **p < 0.01; ***p < 0.001 (E) Inhibitory rates of 7m on the HUVEC migration. (F) Quantitative analysis of the migration ability. *p < 0.05, **p < 0.01; ***p < 0.001, vs. control; n = 3.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Chem