Fig. 2
- ID
- ZDB-FIG-211203-19
- Publication
- Sperotto et al., 2021 - Targeting thymidine phosphorylase inhibition in human colorectal cancer xenografts
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Migration assay in HCT-116 cell over 48 h of exposure to CPBMF-223 and TPI (competitive inhibitor of hTP). Measurement of HCT-116 cell migration (%) over time (0, 4, 8, 12, 24 and 48 h) (A) and representative images of migration after 48 h of treatment (B). DMEM with 10% FBS was used as positive control of migration. Five independent measurements per picture were performed in order to calculate the percentage of migration, considering time 0 of each treatment with 0%. Data were expressed with the mean ± standard error of the mean. Statistical analysis was performed by two-way analysis of variance, followed by Bonferroni post-test. Data significant in relation to positive control (DMEM 10% FBS) at *p < 0.05 and ***p < 0.001. |