Fig 3
- ID
- ZDB-FIG-211201-7
- Publication
- Guan et al., 2021 - Plasma obtained following murine hindlimb ischemic conditioning protects against oxidative stress in zebrafish models through activation of nrf2a and downregulation of duox
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Real-time PCR array revealed that oxidative stress related genes are affected in RIC treated fish.
(A) Zebrafish larvae injected with Ctrl or RIC plasma were incubated at 28°C for the same amount of time as the tailfin cut group was harvested. The fish larvae without tailfin injury were collected for RNA extraction and PCR array analysis. The relative gene expression (fold change, RIC group/ Ctrl group) is shown in the heatmap. The up-regulated genes in RIC treated fish are represented in red (fold>1), while the down-regulated gene are represented in blue (fold<-1). (B) Zebrafish larvae injected with Ctrl or RIC plasma were incubated at 28°C for 16 hours. The tail fin was transected and incubated for 1 hour. The fish larvae with tailfin injury were collected for RNA extraction and PCR array analysis. |