FIGURE

Fig 1

ID

ZDB-FIG-211122-23

Publication

Kikel-Coury et al., 2021 - Identification of astroglia-like cardiac nexus glia that are critical regulators of cardiac development and function

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Fig 1

Adult gfap⁺ cells are conserved across species.

(A) Confocal maximum z-projection from adult zebrafish, mouse, and human ventricle stained with GFAP. Schematics of hearts per species (above) indicate location of imaging. Gfap⁺ cells are present across species. (B) Confocal 10 ?m z-projection of adult Tg(gfap:gfp) ventricles with 3 distinct morphologies of gfap⁺ cells. (C) Quantification of process length between gfap⁺ cell types. (D) Quantification of process number per gfap⁺ cell type. (E) Confocal maximum z-projection from adult Tg(myl7:gfp) ventricles stained with AcTub and GFAP showing localization. Gfap⁺ cells localize with AcTub⁺ axons. Data are represented as mean ± SEM. Scale bar equals 10 ?m. Statistics summarized in S1 Table. See S1 Data for raw data. A, atrium; AcTub, acetylated tubulin; AO, aorta; BA, bulbous arteriosus; LA, left atrium; LV, left ventricle; PA, pulmonary artery; RA, right atrium; RV, right ventricle; SV, sinoatrial valve; V, ventricle.

Expression Data

Genes:	Cerulean GFP
Antibodies:	Ab1-tuba Ab2-gfap
Fish:	co19Tg mi2001Tg
Anatomical Terms:	cardiac conduction system axon cardiac ventricle glial cell (sensu Vertebrata) ventricular myocardium
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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