FIGURE

Fig. 4

ID

ZDB-FIG-211008-4

Publication

Ross et al., 2021 - Generation and Molecular Characterization of Transient tet1/2/3 Zebrafish Knockouts

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Fig. 4

Visualization and analysis of tet1/2/3 KO RRBS data. (a) Left panel: IGV visualization of BAM files in bisulfite mode (CG) over a phylo-DMR (phylotypic stage enhancer) region. Red = methylated cytosine, blue = unmethylated cytosine. Grey boxes represent single reads. Right panel: IGV visualization of BigWig files. Blue bars represent methylation level (mCG/CG). (b) Global mCG/CG levels of two biological replicates of uninjected (wt) and injected (tet1/2/3 KO) 24hpf F0 zebrafish. Methylation values correspond to average mCG/CG level in genomic bins (150 bp). (c) PhyloDMR mCG/CG levels of two biological replicates of uninjected (wt) and injected (tet1/2/3 KO) 24 hpf F0 zebrafish. (d) Heatmap showing locus-specific mCG/CG levels in phyloDMRs

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Meth. Mol. Biol.