FIGURE

Figure 1

ID

ZDB-FIG-210902-270

Publication

Nowik et al., 2021 - The Role of Galanin during Bacterial Infection in Larval Zebrafish

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Figure 1

Galanin deficiency results in higher mortality and bacterial burden after yolk infection. (A,B) Survival rate in mock-injected larvae (non-inf +/+), infected wild-types (inf +/+), infected gal−/− mutants (inf -/-) and infected gal−/− mutants treated with NAX 5055 (inf -/- NAX) after (A) M. marinum or (B) S. aureus yolk infection. (C,D) Bacterial burden in infected wild-type larvae, infected gal−/− mutants and infected gal−/− mutants treated with NAX 5055 after (C) M. marinum or (D) S. aureus yolk infection. Data are combined from three biological replicates (n = 10 larvae/group). * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ns, non-significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT gal^o1/o1
Conditions:	bacterial treatment by injection: Mycobacterium marinum, chemical treatment by injection: Galanin-like peptide bacterial treatment by injection: Mycobacterium marinum bacterial treatment by injection: Staphylococcus aureus bacterial treatment by injection: Staphylococcus aureus, chemical treatment by injection: Galanin-like peptide
Observed In:	whole organism
Stage:	Day 4

Phenotype Detail

Acknowledgments

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