Figure 1
Galanin deficiency results in higher mortality and bacterial burden after yolk infection. (A,B) Survival rate in mock-injected larvae (non-inf +/+), infected wild-types (inf +/+), infected gal−/− mutants (inf -/-) and infected gal−/− mutants treated with NAX 5055 (inf -/- NAX) after (A) M. marinum or (B) S. aureus yolk infection. (C,D) Bacterial burden in infected wild-type larvae, infected gal−/− mutants and infected gal−/− mutants treated with NAX 5055 after (C) M. marinum or (D) S. aureus yolk infection. Data are combined from three biological replicates (n = 10 larvae/group). * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ns, non-significant.