FIGURE

Fig 6

ID

ZDB-FIG-210801-45

Publication

Vong et al., 2021 - The RNA-binding protein Igf2bp3 is critical for embryonic and germline development in zebrafish

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Fig 6

PGC membrane projections show altered behaviour in MZ<italic toggle='yes'>igf2bp3</italic><sup><italic toggle='yes'>la659Tg</italic></sup> mutants.

A. Images of cell membranes of PGCs labelled with a Farnesylated-GFP-nos1 live reporter in bud stage mutant or wild type embryos. B. Quantitation of filopodia and behaviour (persistence, length) in WT and MZigf2bp3^la659Tg PGCs. C. Projection angle relative to their destination, showing an altered skew in maternal igf2bp3^la659Tg PGCs, although the projection parameters, namely numbers, persistence, average and maximum lengths did not appear to be changed. p *<0.05, **<0.01, ***<0.001. N = 27 WT and 26 MZigf2bp3^la659Tg PGCs; number of filopodia = 50 WT and 100 mutant filopodia. Number of PGCs analysed for projection frequency = 25 per genotype; Scale bars, 10 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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