IMAGE

Fig 6

ID: ZDB-IMAGE-210801-51
Publication: Vong et al., 2021 - The RNA-binding protein Igf2bp3 is critical for embryonic and germline development in zebrafish
All Figures: Figures for Vong et al., 2021

Image

Figure Caption

Fig 6 PGC membrane projections show altered behaviour in MZ<italic toggle='yes'>igf2bp3</italic><sup><italic toggle='yes'>la659Tg</italic></sup> mutants.

A. Images of cell membranes of PGCs labelled with a Farnesylated-GFP-nos1 live reporter in bud stage mutant or wild type embryos. B. Quantitation of filopodia and behaviour (persistence, length) in WT and MZigf2bp3^la659Tg PGCs. C. Projection angle relative to their destination, showing an altered skew in maternal igf2bp3^la659Tg PGCs, although the projection parameters, namely numbers, persistence, average and maximum lengths did not appear to be changed. p *<0.05, **<0.01, ***<0.001. N = 27 WT and 26 MZigf2bp3^la659Tg PGCs; number of filopodia = 50 WT and 100 mutant filopodia. Number of PGCs analysed for projection frequency = 25 per genotype; Scale bars, 10 μm.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.