FIGURE

Figure 3

ID

ZDB-FIG-210726-53

Publication

Li et al., 2021 - Gypenosides Alleviate Cone Cell Death in a Zebrafish Model of Retinitis Pigmentosa

Other Figures

All Figure Page

Back to All Figure Page

Figure 3

Significant decreases were found in cone apoptosis in rpgrip1 mutant zebrafish treated with Gyp. (A) Retinal sections of wildtype (WT), untreated (UT) rpgrip1 mutant and Gyp-treated rpgrip1 mutant zebrafish at 6 mpf were stained with TUNEL reagents. Nuclei of apoptotic cone cells were stained in green. DAPI labelled nuclei were stained in blue. (B) Quantification of apoptotic cells in above retinal sections were compared between the wildtype, rpgrip1 mutant and Gyp-treated rpgrip1 mutant zebrafish. Statistical comparisons between individual groups were carried out using one-way ANOVA followed by Bonferroni’s test. Data are displayed as mean ± SEM (n = 6 animals of each group). ** p < 0.01, **** p < 0.0001. INL, inner nuclear layer; ONL, outer nuclear layer.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rpgrip1^fh314/fh314
Observed In:	retinal cone cell retinal cone cell apoptotic process
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)