Figure 2.
- ID
- ZDB-FIG-210709-2
- Publication
- DuMez et al., 2021 - In vivo characterization of carbon dots-bone interactions: toward the development of bone-specific nanocarriers for drug delivery
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C-dots bind to regenerating bones in a concentration-dependent manner. (A) Schematic representation of regeneration experiment in (B)–(E), were C-dot injection followed caudal fin amputation by 1 h. (B–E) Intraperitoneal (B, D) or intravascular (C, E) injection of C-dots before regeneration begins does not label regenerating bone. Images were taken 1 (B, C) and 8 (D, E) days after C-dot injection. (F) Schematic representation of regeneration experiment in (G)–(J), were C-dot injection followed caudal fin amputation by 4 days. (G–J) Intraperitoneal (G, I) or intravascular (H, J) injection of C-dots after caudal fin regeneration has initiated label the bone being regenerated at the time of injection (magenta bracket), but not bone that regenerated after the injection (white bracket). Images were taken 1 (B, C) and 8 (D, E) days after C-dot injection. |