Figure 2

Hericium erinaceus ethanolic extract (HE: 0.5, 1, and 3 mg/L) improved the locomotion pattern and reduced anxiety in the novel tank-diving test (NTT). (A) Representative locomotion-tracking pattern of the control, scopolamine (SCOP: 100 µM), Hericium erinaceus (HE: 0.5, 1, and 3 mg/L) and imipramine (IMP: 20 mg/L) treated groups. (B) Representation of the distance traveled in the top zone in different groups. (C) The time spent by zebrafish in the top/bottom zone of the tank in different groups. (D) Representation of the number of entries in the top zone by zebrafish in the tank in different groups. (E) Representation of the freezing activity by zebrafish in the tank in different groups. (F) Representation of the average velocity of zebrafish in the tank in different groups. (G) Representation of the total distance traveled by zebrafish in the tank in different groups. Values are means ± S.E.M. (n = 10). For Tukey’s post hoc analysis: **** p < 0.0001, *** p < 0.001, ** p < 0.01, and * p < 0.05.