FIGURE

Figure 1

ID

ZDB-FIG-210528-5

Publication

Wang et al., 2021 - Internal modulation of proteolysis in vascular extracellular matrix remodeling: role of ADAM metallopeptidase with thrombospondin type 1 motif 5 in the development of intracranial aneurysm rupture

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Figure 1

Decreased presence of ADAMTS-5 within the aneurysmal wall. (A) Representative immunofluorescence performed on intracranial aneurysm samples harvested from human IA patients after microsurgical clipping, and the normal cerebral artery harvested from a human brain trauma patient, showing the presence of ADAMTS-5. ADAMTS-5 and Collagen IV are displayed in red and green, respectively. Scale bars: 20 μm. (B) CTA identification of aneurysms from the patients included in this study. Human IA sample 1 and sample 2 were obtained from IA patient 1 and patient 2, respectively. (C, D) Representative immunofluorescence performed on mouse samples displaying the healthy control artery and aneurysmal artery for ADAMTS-5. Scale bars: 20 μm. ATS5, ADAMTS-5; COLL IV, Collagen IV.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Aging (Albany NY)