FIGURE

Fig. 7

ID

ZDB-FIG-210519-22

Publication

Zhang et al., 2021 - Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo

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Fig. 7

Hypoxia-reoxygenation imaging in mice hind limb.

Optical imaging of cycling hypoxia in ischemia-reperfusion process in a living mouse via intramuscular injection of HDSF (20 μM, 50 μL, 20 min) in the two hind limbs. The ischemia-reperfusion process was simulated via treating the right limb with a tourniquet for 25 min followed by removing the tourniquet thereafter. a–m images for mouse recorded every 5 min in the ischemia-reperfusion process (1 h); n temporal profiles for average fluorescence intensity in the left (blue) and right (red) limbs. Data were presented as mean ± SD. The results are representative of three independent experiments. λ_ex, 660 nm; λ_em, 710 nm. Source data are available as a Source data file.

Expression Data

Expression Detail

Antibody Labeling

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Phenotype Detail

Acknowledgments

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