FIGURE

Fig 5

ID

ZDB-FIG-210508-54

Publication

Linscheid et al., 2021 - Quantitative proteome comparison of human hearts with those of model organisms

Other Figures

All Figure Page

Back to All Figure Page

Fig 5

Protein abundance profiles for cardiac disease–associated proteins across species.

(a, b) Median protein abundances in LVs are shown for proteins reported to be involved in HCM (panel a) and DCM (panel b) across species. Color scale represents log2-transformed protein intensities (red: highest abundance, turquoise: lowest abundance, and gray: not available). (c) Comparison of protein abundance ratios between atria and ventricle for proteins encoded by 7 genes involved in ARVC. log2 fold change between ventricle and atria are shown. Note that the human ratio profile is best reflected by pig, while profiles in other species differ markedly. Bar height denotes the sample mean, and error bars denote standard deviation. This analysis is based on data presented in S8 Table. ARVC, arrhythmogenic right ventricular cardiomyopathy; DCM, dilated cardiomyopathy; HCM, hypertrophic cardiomyopathy; LV, left ventricle.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.